Bernard Elliot, a poet, and Frances Reardon, a fiction writer, meet at a writers' colony during the summer of 1957 and begin a friendship and correspondence. Bernard, well-born and Harvard-educated, is gregarious, reckless, and passionate; Frances, the precocious daughter of a middle-class Irish family, is circumspect, wry, and more than a little judgmental. What starts as an exploration of faith eventually becomes a romance, a development complicated by Bernard's fall into manic depression and Frances' struggle to decide whether she is strong enough to weather the illness with him for the long term.

The novel is anchored by two deeply imagined, fully inhabited characters who give voice to a love story that is as emotionally powerful as it is intellectually spirited.