Dr. Bruce Banner. Emil Blonsky. One a brilliant scientist, the other an agent for the KBG. Both men whose lives were irrevocably altered by gamma radiation—transforming Banner into the incredible Hulk and Blonsky into the deadly Abomination. For years, the two super-strong creatures have clashed. Now they are brought together for their most deadly confrontation yet.

The Abomination has allied himself with the URSA, an organization dedicated to restoring the Soviet Union—but he is using the URSA to further his own mad quest for vengeance on all those who wronged him in life, including the Hulk!

The Hulk must turn to the American intelligence agency SAFE for assistance against his old foe. But since the head of SAFE is one of the Abomination's targets, even that assistance may not be enough...