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Inside the O'Briens: A Novel

Unabridged Audiobook

Written By: Lisa Genova

Narrated By: Skipp Sudduth

Date: April 2015

Duration: 11 hours 14 minutes


A New York Times bestseller ▪ A Library Journal Best Books of 2015 Pick ▪ A St. Louis Post-Dispatch Best Books of 2015 Pick ▪A GoodReads Top Ten Fiction Book of 2015 ▪ A People Magazine Great Read

From New York Times bestselling author and neuroscientist Lisa Genova comes a “heartbreaking…very human novel” (Matthew Thomas, author of We Are Not Ourselves) that does for Huntington’s disease what her debut novel Still Alice did for Alzheimer’s.

Joe O’Brien is a forty-three-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his family’s lives forever: Huntington’s disease.

Huntington’s is a lethal neurodegenerative disease with no treatment and no cure, and each of Joe’s four children has a 50 percent chance of inheriting their father’s disease. While watching her potential future in her father’s escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. As Joe’s symptoms worsen and he’s eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life “at risk” or learn their fate.

Praised for writing that “explores the resilience of the human spirit” (San Francisco Chronicle), Lisa Genova has once again delivered a novel as powerful and unforgettable as the human insights at its core.


  • Sonja Flynn

    Fantastic!! Couldn't put it down. I recommended this book to all my friends

    1 of 1 people found this review helpful.

  • Claire W.

    Loved it. this book provoked so many emotions in me. I had tears in my eyes, a knot in my throat and butterflies in my tummy. Beautifully written, insightful, really excellent. highly recommended.

  • Cathy B

    Outstanding book about a difficult subject. I had never heard of HD before reading this book. Well narrated and put together

  • Judy Bartlett

    Having a friend with this horrible disease I was interested to find a book about Huntingtons. It is well explained and shows realisticly how members of the family handle the diagnosis and dreaded future. I am hoping this book will bring a new awareness of HD to more of the world and new medications that could lead to a cure.

  • Nancy Krehlik

    Lisa Genova has done it again! She has taken a terrible degenerative disease, explained it well, painted a realistic picture of it, and put it in the middle of a normal, like able family with all of it's everyday challenges, personalities, and foibles. You see the family members grapple with what this diagnosis means to the family as a whole and to each individual. A good read. It is not a "sad" book even though it is a sad situation.

  • Kathleen Matthews

    Difficult to write a review concerning such a sad tale. Huntington Disease is well explained and just plain awful. Enjoyed the family history and the family fun.

Inside the O'Briens: A Novel

by Lisa Genova

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Inside the O'Briens: A Novel, Lisa Genova
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