Can three scrappy, single women of varied ages find happiness in a new travel business specializing in casino junkets? All bets are off when Betty Chance finds a body in a tour bus that arrives at the casino hotel. At fifty, Betty is unemployed, divorced and penniless, after her husband left her for an older, fatter woman. But with her stunningly beautiful niece Lori, she opens Take A Chance Tours, a Chicago-based company specializing in gaming destinations. Betty quickly becomes close friends with Tillie, the perky, effervescent bus driver who happens to be an ex-con. As soon as the tour bus arrives at Moose Lake Bay Resort and Casino in northern Minnesota, Betty and her driver Tillie, discover a dead body in the locked bathroom of their motorcoach. The 350-pound corpse is riddled with stab wounds. With Tillie and Lori’s help, Betty puts her amateur sleuth ability to work and searches for the killer.