God and the Devil have decided to meet again at last, but to do so they must each take human form again. Rome will form the perfect backdrop to their summit.

So an Englishman who has lost his mind; an American couple with death on their minds; a young Argentinian man with living on his mind; a megastar songstress with trouble on her mind; a grouchy priest with too much on his mind... and a dog called Walter, are fated to meet, under the Roman sky.

This is not a who done it. This is a who the hell are they?