Found in the treacherous Strait of Gibraltar, a man who answers only to the name of Christopher Columbus is delivered to a mental institution in Sevilla. Nurse Consuela, a lonely young woman searching for love, who listens to his fantastical tales of adventure and romance day after day, tries desperately to make some sense of why this man has been locked up, and to discover his true identity.

Simultaneously, Emile Germain, an Interpol officer based in France, receives a memo about an enigmatic figure, possibly a dangerous assailant, who is missing from the scene of a crime. All paths lead to Spain, where Germain finds himself on a journey that seems like a wild goose chase. Unbeknownst to him as well as to the doctors at the Sevilla Institute, Emile is unraveling more than just one mystery.